SCHEMBL5344440

SCHEMBL5344440

Cn1cc(OC(=O)Cl)c(CF)n1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.33
GLA P06280 1/20 0.31
KMT2A Q03164 1/20 0.31
LMNA P02545 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16105746 0.85 GAA (0.34) GAA
SCHEMBL2353374 0.78 GAA (0.37) GAALMNAPOLB
SCHEMBL6587153 0.76 POLB (0.39) GAAGLAKMT2ALMNAPOLB
SCHEMBL5983299 0.75 GLA (0.33) GAAGLAKMT2APOLB
SCHEMBL3730626 0.74 GAA (0.48) GAALMNAPOLB
SCHEMBL1135830 0.74 IRAK4 (0.33) GAAGLAKMT2A
SCHEMBL16105736 0.74 GAA (0.42) GAAGLAKMT2ALMNAPOLB
SCHEMBL27694444 0.73
SCHEMBL4655564 0.70 GAA (0.37) GAALMNAPOLB
SCHEMBL14184721 0.70 GAA (0.37) GAAKMT2ALMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1856055-B1 PYRAZOLE CARBOXYLIC ACID ANILIDES, METHOD FOR THE PRODUCTION THEREOF AND AGENTS CONTAINING THEM FOR CONTROLLING PATHOGENIC FUNGI BASF SE (DE) 2014-10-01 EP disclosed
EP-1856055-A1 PYRAZOLE CARBOXYLIC ACID ANILIDES, METHOD FOR THE PRODUCTION THEREOF AND AGENTS CONTAINING THEM FOR CONTROLLING PATHOGENIC FUNGI BASF AKTIENGESELLSCHAFT (DE) 2007-11-21 EP disclosed
WO-2006087343-A1 PYRAZOLE CARBOXYLIC ACID ANILIDES, METHOD FOR THE PRODUCTION THEREOF AND AGENTS CONTAINING THEM FOR CONTROLLING PATHOGENIC FUNGI BASF AKTIENGESELLSCHAFT (DE) 2006-08-24 WO disclosed