Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.59 |
| ▸ | FLT1 | P17948 | 2/20 | 0.59 |
| ▸ | FLT4 | P35916 | 2/20 | 0.59 |
| ▸ | RET | P07949 | 1/20 | 0.52 |
| ▸ | SYK | P43405 | 2/20 | 0.50 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 5/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | QPCT | Q16769 | 1/20 | 0.45 |
| ▸ | VCP | P55072 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5334189 | 0.93 | FLT1 (0.52) | KDRFLT1FLT4RETSYK | |
| SCHEMBL5336694 | 0.93 | FLT1 (0.52) | KDRFLT1FLT4RETSYK | |
| SCHEMBL5334372 | 0.92 | KDR (0.59) | KDRFLT1FLT4RETSYK | |
| SCHEMBL5341184 | 0.91 | FLT1 (0.50) | KDRFLT1FLT4RETSYK | |
| SCHEMBL5318108 | 0.91 | FLT1 (0.50) | KDRFLT1FLT4RETSYK | |
| SCHEMBL5433991 | 0.91 | RAF1 (0.52) | KDRFLT1FLT4RETTNIK | |
| SCHEMBL5338278 | 0.91 | KDR (0.51) | KDRFLT1FLT4RETSYK | |
| SCHEMBL14466940 | 0.91 | KDR (0.49) | KDRFLT1FLT4RETSYK | |
| SCHEMBL5343446 | 0.91 | FLT1 (0.49) | KDRFLT1FLT4RETSYK | |
| SCHEMBL5339857 | 0.91 | FLT1 (0.49) | KDRFLT1FLT4RETSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | disclosed |
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | disclosed |