SCHEMBL5344528

SCHEMBL5344528

CC12CCCCC1C1C=CC(CC2)C1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CDK5 Q00535 1/20 0.32
CDK5R1 Q15078 1/20 0.32
NR1I3 Q14994 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL986455 0.81 KDM4E (0.30)
SCHEMBL5835426 0.72
SCHEMBL5862336 0.67
SCHEMBL5341895 0.67 CYP19A1 (0.30)
SCHEMBL5862305 0.66
SCHEMBL14732113 0.62
SCHEMBL5862132 0.60
SCHEMBL4220894 0.60 EBP (0.42) CDK5CDK5R1NR1I3
SCHEMBL27477684 0.60 NR1I3 (0.40) CDK5CDK5R1NR1I3
SCHEMBL5345474 0.59 EPAS1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7186448-B2 Composition and method for temporarily fixing solid JSR CORPORATION (JP) 2007-03-06 US disclosed
US-20060275939-A1 Composition and method for temporarily fixing solids JSR CORPORATION (JP) 2006-12-07 US disclosed
US-7015293-B2 Cycloolefin addition copolymer and optical transparent material JSR CORPORATION (JP) 2006-03-21 US disclosed
US-20050171310-A1 Cycloolefin addition copolymer and optical transparent material JSR CORPORATION (JP) 2005-08-04 US disclosed
EP-1538169-A1 CYCLOOLEFIN ADDITION COPOLYMER AND OPTICAL TRANSPARENT MATERIAL JSR Corporation (JP) 2005-06-08 EP disclosed
EP-1522567-A1 COMPOSITION AND METHOD FOR TEMPORARILY FIXING SOLID JSR Corporation (JP) 2005-04-13 EP disclosed
US-20040185187-A1 Composition and method for temporarily fixing solid JSR CORPORATION (JP) 2004-09-23 US disclosed