Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.43 |
| ▸ | PPARA | Q07869 | 10/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4892245 | 0.94 | PPARG (0.44) | PPARGPPARAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5359040 | 0.87 | PPARG (0.52) | PPARGPPARA | |
| SCHEMBL5358052 | 0.86 | PPARG (0.49) | PPARGPPARA | |
| SCHEMBL5353221 | 0.84 | PPARG (0.52) | PPARGPPARA | |
| SCHEMBL5354968 | 0.83 | PPARG (0.47) | PPARGPPARA | |
| SCHEMBL5351106 | 0.82 | PPARG (0.40) | PPARGPPARA | |
| SCHEMBL5354283 | 0.79 | PPARG (0.45) | PPARGPPARA | |
| SCHEMBL5366174 | 0.78 | PPARG (0.50) | PPARGPPARA | |
| SCHEMBL5359236 | 0.77 | PPARG (0.40) | PPARGPPARA | |
| SCHEMBL5355221 | 0.77 | PPARG (0.42) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7282501-B2 | Modulators of peroxisome proliferator activated receptors (PPAR) | ELI LILLY AND COMPANY (US) | 2007-10-16 | — | — | US | claimed |