SCHEMBL5346090

SCHEMBL5346090

COc1ccc(C(=O)O[C@H]2CC[C@@]3(C)C(=CC[C@H]4[C@@H]5CC[C@H]([C@H](C)CCCC(C)C)[C@@]5(C)CC[C@@H]43)C2)cc1

nearest known ligand 0.69

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
POLA1 P09884 1/20 0.69
CYP46A1 Q9Y6A2 2/20 0.67
OSBP P22059 3/20 0.63
USP2 O75604 2/20 0.63
RORC P51449 2/20 0.63
LMNA P02545 1/20 0.63
ABCB1 P08183 1/20 0.63
OSBP2 Q969R2 1/20 0.63
NR1H3 Q13133 4/20 0.56
NPC1L1 Q9UHC9 2/20 0.55
NPC1 O15118 1/20 0.55
CYP1A2 P05177 1/20 0.55
GBA1 P04062 2/20 0.55
UGCG Q16739 2/20 0.55
GBA2 Q9HCG7 2/20 0.55
PLA2G2A P14555 1/20 0.54
GRIN1 Q05586 1/20 0.54
GRIN2A Q12879 1/20 0.54
EPHA2 P29317 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17933650 1.00 POLA1 (0.69) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL5346093 1.00 POLA1 (0.69) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL9558936 0.96 POLA1 (0.63) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL12290847 0.96 POLA1 (0.63) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL11288161 0.92 POLA1 (0.70) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL17270372 0.92 POLA1 (0.70) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL12154332 0.92 POLA1 (0.70) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL14138204 0.92 POLA1 (0.70) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL18904679 0.92 POLA1 (0.70) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL9446914 0.92 POLA1 (0.70) POLA1CYP46A1OSBPUSP2RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023142890-A1 SYNTHESIS METHOD FOR HIGH-PURITY CHOLESTEROL 华东师范大学 2023-08-03 WO disclosed
WO-2023142888-A1 METHOD FOR SYNTHESIZING HIGH-PURITY PLANT-DERIVED CHOLESTEROL 华东师范大学 2023-08-03 WO disclosed
US-7186448-B2 Composition and method for temporarily fixing solid JSR CORPORATION (JP) 2007-03-06 US disclosed
US-20060275939-A1 Composition and method for temporarily fixing solids JSR CORPORATION (JP) 2006-12-07 US disclosed
EP-1522567-A1 COMPOSITION AND METHOD FOR TEMPORARILY FIXING SOLID JSR Corporation (JP) 2005-04-13 EP disclosed
US-20040185187-A1 Composition and method for temporarily fixing solid JSR CORPORATION (JP) 2004-09-23 US disclosed