Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.51 |
| ▸ | CALCR | P30988 | 10/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.50 |
| ▸ | APLNR | P35414 | 1/20 | 0.48 |
| ▸ | RAMP3 | O60896 | 6/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.45 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5346255 | 1.00 | F2 (0.51) | F2CALCRHCRTR1HCRTR2APLNR | |
| SCHEMBL30658556 | 0.88 | F2 (0.50) | F2CALCRAPLNR | |
| SCHEMBL31573968 | 0.88 | C5AR1 (0.50) | F2CALCRHCRTR1HCRTR2RAMP3 | |
| SCHEMBL29662390 | 0.88 | CALCR (0.54) | CALCRHCRTR1HCRTR2RAMP3CXCR4 | |
| SCHEMBL29384601 | 0.85 | SLC6A2 (0.52) | F2CALCRAPLNRRAMP3 | |
| SCHEMBL29641693 | 0.85 | SLC6A2 (0.48) | F2CALCRAPLNRRAMP3 | |
| SCHEMBL30906480 | 0.85 | CALCR (0.57) | F2CALCRHCRTR1HCRTR2APLNR | |
| SCHEMBL31573972 | 0.84 | C5AR1 (0.48) | F2CALCRHCRTR1HCRTR2CXCR4 | |
| SCHEMBL29674857 | 0.84 | F2 (0.52) | F2CALCRAPLNRKEAP1CRHR1 | |
| SCHEMBL31452900 | 0.84 | CALCRL (0.54) | F2CALCRHCRTR1HCRTR2APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7198919-B1 | Use of alpha factor sequences in yeast expression systems | GENENTECH, INC. (US) | 2007-04-03 | — | — | US | disclosed |
| EP-0123544-A2 | Process for expressing heterologous protein in yeast, expression vehicles and yeast organisms therefor | GENENTECH, INC. (US) | 1984-10-31 | — | — | EP | disclosed |