Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 11/20 | 0.46 |
| ▸ | AKT2 | P31751 | 10/20 | 0.46 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.46 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5348322 | 0.88 | MAPK13 (0.44) | KDM4ELMNAGAAL3MBTL1ADORA2A | |
| SCHEMBL5341786 | 0.86 | AKT1 (0.48) | KDM4ELMNAGAAL3MBTL1ADORA2A | |
| SCHEMBL5360784 | 0.80 | KDM4E (0.47) | KDM4ELMNAGAAL3MBTL1ADORA2A | |
| SCHEMBL5322377 | 0.77 | AKT1 (0.50) | KDM4ELMNAGAAL3MBTL1AKT1 | |
| SCHEMBL5341130 | 0.75 | ADORA2A (0.39) | LMNAADORA2AAKT1AKT2ALDH1A1 | |
| SCHEMBL5342418 | 0.74 | DPP4 (0.56) | KDM4ELMNAGAAL3MBTL1AKT1 | |
| SCHEMBL5318363 | 0.73 | AKT1 (0.62) | KDM4ELMNAGAAL3MBTL1AKT1 | |
| SCHEMBL5320557 | 0.73 | AKT1 (0.45) | AKT1AKT2ALDH1A3NR1I3 | |
| SCHEMBL5356111 | 0.73 | AKT1 (0.41) | KDM4ELMNAGAAL3MBTL1ADORA2A | |
| SCHEMBL5478849 | 0.72 | AKT1 (0.55) | KDM4ELMNAGAAL3MBTL1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | claimed |
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | disclosed |