SCHEMBL534668

SCHEMBL534668

C#CCOCC1(C)COC2(CCCCC2)N1.[NaH]

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL534461 0.99 KDM4E (0.36) KDM4EALDH1A1MAPT
SCHEMBL534667 0.96 KDM4E (0.34) KDM4EALDH1A1MAPT
SCHEMBL9779046 0.77 KDM4E (0.42) KDM4EALDH1A1MAPT
SCHEMBL534610 0.70 KDM4E (0.58) KDM4EALDH1A1MAPT
SCHEMBL18335401 0.65
SCHEMBL18335384 0.65
SCHEMBL17136139 0.63
SCHEMBL22686876 0.63
SCHEMBL3886463 0.63 KDM4E (0.47) KDM4EALDH1A1MAPT
SCHEMBL9873656 0.63 KDM4E (0.47) KDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2185518-B1 Aryloxyacetamide derivatives and their use as fungicides SYNGENTA PARTICIPATIONS AG (CH) 2012-02-08 EP disclosed
EP-2185518-A2 SATURATED AND INSATURATED BI- OR TRICYCLIC ARYLOXYACETAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES Syngenta Participations AG (CH) 2010-05-19 EP disclosed
WO-2009030467-A2 SATURATED AND INSATURATED BI- OR TRICYCLIC ARYLOXYACETAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES SYNGENTA PARTICIPATIONS AG, (CH) 2009-03-12 WO disclosed