Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21133899 | 0.93 | MAPK14 (0.75) | MAPK14 | |
| SCHEMBL5202123 | 0.92 | MAPK14 (0.76) | MAPK14 | |
| SCHEMBL5350273 | 0.92 | MAPK14 (0.73) | MAPK14 | |
| SCHEMBL5352532 | 0.87 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL4499746 | 0.85 | MAPK14 (0.79) | MAPK14 | |
| SCHEMBL5360018 | 0.85 | MAPK14 (0.84) | MAPK14 | |
| SCHEMBL5201196 | 0.85 | MAPK14 (0.78) | MAPK14 | |
| SCHEMBL5364410 | 0.84 | MAPK14 (0.85) | MAPK14 | |
| SCHEMBL14357732 | 0.84 | MAPK14 (0.57) | MAPK14 | |
| SCHEMBL14270492 | 0.83 | MAPK14 (0.63) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238712-B2 | Indole-type derivatives as inhibitors of p38 kinase | SCIOS, INC. (US) | 2007-07-03 | — | — | US | claimed |