Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | MTOR | P42345 | 2/20 | 0.53 |
| ▸ | LSS | P48449 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4020664 | 0.81 | IDO1 (0.56) | HDAC3HDAC1HDAC2HDAC6HDAC10 | |
| SCHEMBL24575984 | 0.81 | MTOR (0.69) | HDAC3HDAC1HDAC2HDAC6HDAC10 | |
| SCHEMBL2186485 | 0.80 | MTOR (0.48) | HDAC3HDAC1HDAC2HDAC6HDAC10 | |
| Hydrochloric Acid SCHEMBL30996799 | 0.80 | IDO1 (0.57) | HDAC3HDAC1HDAC2HDAC6HDAC10 | |
| SCHEMBL1695141 | 0.79 | MTOR (0.58) | HDAC3HDAC1HDAC2HDAC6HDAC10 | |
| SCHEMBL2629356 | 0.78 | LSS (0.59) | HDAC3HDAC1HDAC2HDAC6HDAC10 | |
| SCHEMBL3897948 | 0.78 | CYP2C9 (0.59) | HDAC3HDAC1HDAC2HDAC6HDAC10 | |
| SCHEMBL21387743 | 0.78 | HDAC3 (0.59) | HDAC3HDAC1HDAC2HDAC6HDAC10 | |
| SCHEMBL17777671 | 0.76 | IDO1 (0.50) | HDAC3HDAC1HDAC2HDAC6HDAC10 | |
| SCHEMBL4576236 | 0.75 | MTOR (0.54) | HDAC3HDAC1HDAC2HDAC6HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007123818-A2 | ORGANIC NITRIC OXIDE ENHANCING SALTS OF PROSTAGLANDINS, COMPOSITIONS AND METHODS OF USE | NITROMED, INC. (US) | 2007-11-01 | — | — | WO | disclosed |