Methane

Methane

SCHEMBL5347165

C.CCN(CC)c1nc(NO)nc(N(O)O)n1

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CA1 P00915 3/20 0.38
CA2 P00918 3/20 0.38
CA9 Q16790 3/20 0.38
RAB9A P51151 1/20 0.38
ALOX15 P16050 2/20 0.35
USP2 O75604 1/20 0.35
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MAPT P10636 1/20 0.33
SLC29A1 Q99808 1/20 0.33
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.31
CRHR1 P34998 2/20 0.31
KDM4E B2RXH2 1/20 0.30
CFTR P13569 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3125055 0.86 TSHR (0.42) TSHRTDP1CA1CA2CA9
Methyl Alcohol SCHEMBL6392642 0.84 TSHR (0.41) TSHRTDP1CA1CA2CA9
Methane SCHEMBL4849691 0.79 KDM4E (0.33) POLBKDM4E
SCHEMBL14557576 0.78 CA1 (0.43) TSHRTDP1CA1CA2CA9
SCHEMBL14557570 0.78 GAA (0.52) TSHRCA1CA2CA9MEN1
SCHEMBL5490930 0.75 MAPT (0.56) TSHRTDP1CA1CA2CA9
SCHEMBL278886 0.74 MEN1 (0.40) TSHRTDP1CA1CA2CA9
SCHEMBL14561892 0.73 CA1 (0.43) TSHRTDP1CA1CA2CA9
SCHEMBL3822649 0.72 KDM4E (0.37) KDM4E
SCHEMBL2741119 0.72 TDP1 (0.64) TSHRTDP1CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7229751-B2 Silver salt photothermographic dry imaging material and image forming method using the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-06-12 US disclosed
US-20050136366-A1 Silver salt photothermographic dry imaging material and image forming method using the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2005-06-23 US disclosed