Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 16/20 | 0.62 |
| ▸ | CTSD | P07339 | 10/20 | 0.62 |
| ▸ | BCHE | P06276 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5347417 | 1.00 | BACE1 (0.62) | BACE1CTSDBCHE | |
| Trifluoroacetic Acid SCHEMBL3349179 | 0.96 | BACE1 (0.58) | BACE1CTSDBCHE | |
| SCHEMBL5349744 | 0.92 | BACE1 (0.61) | BACE1CTSD | |
| SCHEMBL3349185 | 0.85 | BACE1 (0.49) | BACE1CTSDBCHE | |
| SCHEMBL6698501 | 0.80 | BACE1 (0.77) | BACE1CTSDBCHE | |
| SCHEMBL3351647 | 0.79 | BACE1 (0.63) | BACE1CTSDBCHE | |
| SCHEMBL3351639 | 0.79 | BACE1 (0.63) | BACE1CTSDBCHE | |
| SCHEMBL3348470 | 0.78 | BACE1 (0.45) | BACE1CTSD | |
| SCHEMBL3356997 | 0.76 | BACE1 (0.68) | BACE1CTSDBCHE | |
| SCHEMBL3357005 | 0.76 | BACE1 (0.68) | BACE1CTSDBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213407-A1 | Compounds to treat Alzheimer's disease | ELAN PHARMACEUTICALS AND PHARMACIA & UPJOHN COMPANY LLC | 2007-09-13 | — | — | US | claimed |
| US-7214715-B2 | Compounds to treat Alzheimer's disease | PHARMACIA & UPJOHN (US) | 2007-05-08 | — | — | US | claimed |
| US-20020128255-A1 | Compounds to treat alzheimer's disease | PHARMACIA & UPJOHN COMPANY | 2002-09-12 | — | — | US | claimed |
| US-7176242-B2 | N,N′-substituted-1,3-diamino-2-hydroxypropane derivatives | ELAN PHARMACEUTICALS, INC. (US) | 2007-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128255-A1 | Compounds to treat alzheimer's disease | PSEN2, PSEN1, APP | BACE1 4/4885CTSD 2080/4885BCHE 12/4885 |
| US-20070213407-A1 | Compounds to treat Alzheimer's disease | PSEN2, PSEN1, CHAT | BACE1 7/4885CTSD 1351/4885BCHE 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.