SCHEMBL5347884

SCHEMBL5347884

COC(=O)C1(C)C=CC=CC1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CYP3A4 P08684 1/20 0.33
MAPK1 P28482 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7535171 0.89
SCHEMBL31259143 0.85
SCHEMBL8521845 0.80
SCHEMBL28231867 0.79 MAPK1 (0.32) MEN1KMT2ACYP3A4MAPK1NPSR1
SCHEMBL27677591 0.79
SCHEMBL13157265 0.79 POLB (0.34) MEN1KMT2A
SCHEMBL28251918 0.79
SCHEMBL1767501 0.78 CYP3A4 (0.31) CYP3A4
SCHEMBL1044296 0.78 CYP3A4 (0.34) CYP3A4
SCHEMBL6106227 0.78 NPSR1 (0.31) NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3468555-B1 COMPOSITIONS FOR USE IN TREATING BACTERIAL INFECTIONS VERSITECH LTD (HK) 2023-08-09 EP disclosed
US-7196150-B2 Method for radical polymerisation in the presence of a chain transfer agent BASF AKTIENGESELLSCHAFT (DE) 2007-03-27 US disclosed
US-20060058478-A1 Method for radical polymerisation in the presence of a chain transfer agent BASF AKTIENGESELLSCHAFT (DE) 2006-03-16 US disclosed