SCHEMBL534802

SCHEMBL534802

C=CC(=O)OCCC[Si](CC)(CC)OCC

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.56
HPGD P15428 1/20 0.56
ALDH1A1 P00352 4/20 0.52
CYP3A4 P08684 2/20 0.52
TP53 P04637 3/20 0.43
HIF1A Q16665 3/20 0.43
HSD17B10 Q99714 1/20 0.43
THRB P10828 2/20 0.41
ATM Q13315 1/20 0.38
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HCAR2 Q8TDS4 3/20 0.34
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16537460 0.95 TSHR (0.55) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL16286653 0.94 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL16537821 0.94 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL7878189 0.93 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL16537680 0.92 TSHR (0.56) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL16537786 0.90 TSHR (0.50) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL16537255 0.89 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL16537909 0.88 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL16536604 0.87 TSHR (0.53) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL28017844 0.86 TSHR (0.60) TSHRHPGDALDH1A1CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250019536-A1 STRESS REDUCING AGENT AND RESIN COMPOSITION KANEKA CORPORATION (JP) 2025-01-16 US disclosed
US-20250011596-A1 SILICONE CORE ACRYLIC SHELL IMPACT MODIFIERS CONTAINING PHOSPHORUS ROHM & HAAS (US) 2025-01-09 US disclosed
EP-4444774-A1 SILICONE CORE ACRYLIC SHELL IMPACT MODIFIERS CONTAINING PHOSPHORUS Rohm and Haas Company (US) 2024-10-16 EP disclosed
EP-4446352-A1 WATER-BASED COATING Kaneka Corporation (JP) 2024-10-16 EP disclosed
US-20240327671-A1 WATER-BASED COATING KANEKA CORPORATION (JP) 2024-10-03 US disclosed
CN-118369388-A Water paint 株式会社钟化 2024-07-19 CN disclosed
WO-2023190135-A1 STRESS REDUCING AGENT AND RESIN COMPOSITION 株式会社カネカ 2023-10-05 WO disclosed
WO-2023106317-A1 WATER-BASED COATING 株式会社カネカ 2023-06-15 WO disclosed
WO-2023107523-A1 SILICONE CORE ACRYLIC SHELL IMPACT MODIFIERS CONTAINING PHOSPHORUS ROHM AND HAAS COMPANY (US) 2023-06-15 WO disclosed
CN-110536932-B Polyorganosiloxane-containing rubber latex, process for producing the same, and polyorganosiloxane-containing rubber graft polymer 三菱化学株式会社 2022-12-23 CN disclosed
US-20090140284-A1 Transparent Inorganic Oxide Dispersion and Iorganic Oxide Particle-Containing Resin Composition, Composition for Sealing Light Emitting Element and Light Emitting element, Hard Coat Film and Optical Functional Film and Optical Component, and Method for Producing Inorganic Oxide Pariticle-Containing Resin SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2009-06-04 US disclosed
EP-1950239-A1 TRANSPARENT INORGANIC-OXIDE DISPERSION, RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES, COMPOSITION FOR ENCAPSULATING LUMINESCENT ELEMENT, LUMINESCENT ELEMENT, HARD COAT, OPTICAL FUNCTIONAL FILM, OPTICAL PART, AND PROCESS FOR PRODUCING RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2008-07-30 EP disclosed
US-20070260008-A1 Silica-Containing Silicone Resin Composition and Its Molded Product NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2007-11-08 US disclosed
US-6331373-B1 CHARGE STABILITY AND FLUIDITY NIPPON SHOKUBAI CO., LTD. (JP) 2001-12-18 US disclosed
EP-0708143-B1 Polyvinyl chloride based resin composition and products derived therefrom SEKISUI AMERICA CORP (US) 2000-01-05 EP disclosed
US-5700874-A CONJUGATED DIENE/VINYLAROMATIC HYDROCARBON COPOLYMER MODIFIED WITH ALKOXYSILANE BRIDGESTONE CORPORATION (JP) 1997-12-23 US disclosed
EP-0708143-A1 Polyvinyl chloride based resin composition and products derived therefrom SEKISUI AMERICA CORPORATION (US) 1996-04-24 EP disclosed
US-5414065-A Polymer comprising fluoroalkyl group, a method of preparation thereof, a surface active agent, a surface treatment agent and a coating composition NOF CORPORATION (JP) 1995-05-09 US disclosed
US-5324803-A End groups derived from fluoroalkanoyl peroxide; oil and water repellent NOF CORPORATION (JP) 1994-06-28 US disclosed
EP-0537669-A1 A polymer comprising fluoroalkyl group, a method of preparation thereof, a surface active agent, a surface treatment agent and a coating composition NOF CORPORATION (JP) 1993-04-21 EP disclosed