Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 17/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 17/20 | 0.64 |
| ▸ | ADORA2B | P29275 | 14/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15653932 | 0.90 | ADORA2A (0.64) | ADORA2AADORA1ADORA2BADORA3KDM4E | |
| SCHEMBL30254269 | 0.88 | ADORA2A (0.66) | ADORA2AADORA1ADORA2BADORA3LMNA | |
| Ethyl Acetate SCHEMBL23885365 | 0.86 | ADORA2A (0.53) | ADORA2AADORA1ADORA2BADORA3FBP1 | |
| Ethyl Acetate SCHEMBL30254532 | 0.86 | ADORA2A (0.53) | ADORA2AADORA1ADORA2BADORA3FBP1 | |
| SCHEMBL25223774 | 0.84 | ADORA2A (0.59) | ADORA2AADORA1ADORA2BADORA3FBP1 | |
| SCHEMBL23885221 | 0.81 | ADORA2A (0.69) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL30052722 | 0.81 | ADORA2A (0.69) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL5039892 | 0.80 | ADORA2A (0.64) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL1755068 | 0.79 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL30254658 | 0.77 | ADORA2A (0.51) | ADORA2AADORA1ADORA2BADORA3FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223833-B1 | Peptide nucleic acid conjugates | ISIS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| EP-0804456-B1 | PEPTIDE NUCLEIC ACID CONJUGATES | ISIS PHARMACEUTICALS INC (US) | 2002-08-21 | — | — | EP | disclosed |
| EP-0804456-A4 | PEPTIDE NUCLEIC ACID CONJUGATES | ISIS PHARMACEUTICALS INC (US) | 1999-05-19 | — | — | EP | disclosed |
| EP-0804456-A1 | PEPTIDE NUCLEIC ACID CONJUGATES | ISIS PHARMACEUTICALS, INC. (US) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996011205-A9 | PEPTIDE NUCLEIC ACID CONJUGATES | — | 1996-05-30 | — | — | WO | disclosed |
| WO-1996011205-A1 | PEPTIDE NUCLEIC ACID CONJUGATES | ISIS PHARMACEUTICALS, INC. (US) | 1996-04-18 | — | — | WO | disclosed |