Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.53 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.53 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.53 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.53 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.53 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.53 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.53 |
| ▸ | RAD52 | P43351 | 3/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28244601 | 1.00 | KMT2A (0.53) | KMT2ASMN1; SMN2HTTHSP90AA1RAD52 | |
| Bromide SCHEMBL22027189 | 1.00 | KMT2A (0.53) | KMT2ASMN1; SMN2HTTHSP90AA1RAD52 | |
| Bromide SCHEMBL534904 | 1.00 | KMT2A (0.53) | KMT2ASMN1; SMN2HTTHSP90AA1RAD52 | |
| Bromide SCHEMBL17027659 | 1.00 | KMT2A (0.53) | KMT2ASMN1; SMN2HTTHSP90AA1RAD52 | |
| Bromide SCHEMBL3800991 | 1.00 | KMT2A (0.53) | KMT2ASMN1; SMN2HTTHSP90AA1RAD52 | |
| Bromide SCHEMBL22027172 | 1.00 | KMT2A (0.53) | KMT2ASMN1; SMN2HTTHSP90AA1RAD52 | |
| SCHEMBL5297852 | 0.98 | CHRM2 (0.52) | KMT2ASMN1; SMN2HTTHSP90AA1RAD52 | |
| SCHEMBL4058948 | 0.98 | CHRM2 (0.52) | KMT2ASMN1; SMN2HTTHSP90AA1RAD52 | |
| SCHEMBL5301397 | 0.98 | CHRM2 (0.52) | KMT2ASMN1; SMN2HTTHSP90AA1RAD52 | |
| Bromide SCHEMBL14896254 | 0.98 | KMT2A (0.50) | KMT2ASMN1; SMN2HTTHSP90AA1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2931853-A1 | IONIC LIQUIDS AS LUBRICATING OIL BASE STOCKS, COBASE STOCKS AND MULTIFUNCTIONAL FUNCTIONAL FLUIDS | ExxonMobil Research and Engineering Company (US) | 2015-10-21 | — | — | EP | disclosed |
| WO-2014092953-A1 | IONIC LIQUIDS AS LUBRICATING OIL BASE STOCKS, COBASE STOCKS AND MULTIFUNCTIONAL FUNCTIONAL FLUIDS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2014-06-19 | — | — | WO | disclosed |
| EP-1538183-B1 | THERMOPLASTIC FILM, THERMOPLASTIC RESIN COMPOSITION, AND PHYLLOSILICATE | TEIJIN LTD (JP) | 2007-10-31 | — | — | EP | disclosed |
| US-7189782-B2 | Thermoplastic film, thermoplastic resin composition, and phyllosilicate | TEIJIN LIMITED (JP) | 2007-03-13 | — | — | US | disclosed |
| EP-1538183-A1 | THERMOPLASTIC FILM, THERMOPLASTIC RESIN COMPOSITION, AND PHYLLOSILICATE | TEIJIN LIMITED (JP) | 2005-06-08 | — | — | EP | disclosed |
| US-20050089698-A1 | Thermoplastic film, thermoplastic resin composition, and phyllosilicate | TEIJIN LIMITED (JP) | 2005-04-28 | — | — | US | disclosed |
| CN-1596287-A | Thermoplastic film, thermoplastic resin composition, and phyllosilicate | TEIJIN LTD (JP) | 2005-03-16 | — | — | CN | disclosed |