Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 3/20 | 0.65 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MMP13 | P45452 | 2/20 | 0.56 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | STAT1 | P42224 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | ACP1 | P24666 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14375443 | 0.89 | SCD (0.69) | SCDDYRK1AMAPTHTTGAA | |
| SCHEMBL16732745 | 0.86 | DYRK1A (0.78) | DYRK1AMAPTHTTKMT2AMMP13 | |
| SCHEMBL5357648 | 0.83 | SCD (0.62) | SCDDYRK1AMAPTHTTHPGD | |
| SCHEMBL16317399 | 0.82 | SCD (0.54) | SCDDYRK1AMAPTHTTGAA | |
| SCHEMBL5358084 | 0.82 | SCD (0.50) | SCDDYRK1AMAPTHTTGAA | |
| SCHEMBL5352456 | 0.82 | NPC1 (0.61) | SCDDYRK1AMAPTHTTGAA | |
| SCHEMBL5350882 | 0.81 | PTPN1 (0.64) | SCDDYRK1AMAPTHPGDKMT2A | |
| SCHEMBL14375386 | 0.80 | SMN1; SMN2 (0.72) | SCDMAPTHTTKMT2ASMN1; SMN2 | |
| SCHEMBL4921041 | 0.79 | SCD (1.00) | SCDMAPTHPGDKMT2AMMP13 | |
| SCHEMBL5343556 | 0.78 | CYP3A4 (0.72) | SCDMAPTHTTGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249600-A1 | CHEMICAL COMPOUNDS | CHEUNG MUI | 2007-10-25 | — | — | US | disclosed |
| US-7238813-B2 | Chemical compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-20040082583-A1 | Chemical compounds | SMITHKLINE BEECHAM CORPORATION | 2004-04-29 | — | — | US | disclosed |
| EP-1341771-A2 | BENZIMIDAZOLE DERIVATIVES USEFUL AS TIE-2 AND/OR VEGFR-2 INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002044156-A2 | BENZIMIDAZOLE DERIVATIVES USEFUL AS TIE-2 AND/OR VEGFR-2 INHIBITORS | GLAXO GROUP LIMITED (GB) | 2002-06-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249600-A1 | CHEMICAL COMPOUNDS | TIE1, KDR, FLT4 | SCD 4477/4885DYRK1A 2174/4885MAPT 2991/4885 |
| US-20040082583-A1 | Chemical compounds | TIE1, KDR, FLT4 | SCD 4477/4885DYRK1A 2174/4885MAPT 2991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.