Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.53 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.52 |
| ▸ | VNN1 | O95497 | 4/20 | 0.50 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.50 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.50 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.49 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.49 |
| ▸ | NOS1 | P29475 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2774523 | 0.88 | FFAR1 (0.52) | FFAR1FFAR4DPP7SCN8AVNN1 | |
| SCHEMBL410123 | 0.81 | SCN8A (0.57) | DPP7SCN8AVNN1MEP1AMEP1B | |
| SCHEMBL406503 | 0.80 | SCN8A (0.51) | FFAR1FFAR4DPP7SCN8AVNN1 | |
| SCHEMBL3491515 | 0.80 | FFAR1 (0.72) | FFAR1FFAR4LMNACNR1 | |
| SCHEMBL3197343 | 0.78 | SLC2A4 (0.53) | LMNAFOLH1 | |
| SCHEMBL3461756 | 0.78 | ERCC1 (0.60) | FFAR1FFAR4VNN1MEP1AMEP1B | |
| SCHEMBL2224632 | 0.77 | MEN1 (0.64) | FFAR1FFAR4FOLH1MAOA | |
| SCHEMBL3206273 | 0.77 | S1PR5 (0.47) | FOLH1 | |
| SCHEMBL5474619 | 0.77 | NAMPT (0.47) | FFAR1FOLH1MAOAMAOB | |
| SCHEMBL5939993 | 0.77 | CHRM2 (0.63) | LMNAFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414341-A2 | OXADIAZOLE DERIVATIVES | Merck Serono SA (CH) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010115751-A2 | OXADIAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2010-10-14 | — | — | WO | disclosed |