Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 10/20 | 0.37 |
| ▸ | AKT2 | P31751 | 9/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | NR1I3 | Q14994 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5349454 | 0.80 | CNR1 (0.41) | MAPK13MAPK12MAPK11MAPK14AKT1 | |
| SCHEMBL5337696 | 0.78 | MAPK13 (0.41) | MAPK13MAPK12MAPK11MAPK14AKT1 | |
| SCHEMBL5322344 | 0.74 | AKT1 (0.55) | MAPK13MAPK12MAPK11MAPK14AKT1 | |
| SCHEMBL5318363 | 0.70 | AKT1 (0.62) | MAPK13MAPK12MAPK11MAPK14AKT1 | |
| SCHEMBL5348895 | 0.68 | MAPK13 (0.41) | MAPK13MAPK12MAPK11MAPK14AKT1 | |
| SCHEMBL5263183 | 0.68 | AKT1 (0.49) | MAPK13MAPK12MAPK11MAPK14AKT1 | |
| SCHEMBL5324610 | 0.67 | AKT1 (0.44) | AKT1AKT2PTGS2CNR1KDM4E | |
| SCHEMBL5263026 | 0.64 | AKT1 (0.43) | MAPK13MAPK12MAPK11MAPK14AKT1 | |
| SCHEMBL5263277 | 0.63 | AKT1 (0.42) | MAPK13MAPK12MAPK11MAPK14AKT1 | |
| SCHEMBL3408632 | 0.61 | SLC6A2 (0.63) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | claimed |
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | disclosed |