Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL891089 | 0.70 | TYMP (0.46) | ALDH1A1HPGDKDM4EMAPTTSHR | |
| SCHEMBL95750 | 0.69 | MEN1 (0.44) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL24016772 | 0.69 | MEN1 (0.49) | ALDH1A1HPGDKDM4ECYP1A2CYP2D6 | |
| SCHEMBL2360239 | 0.68 | TYMP (0.44) | ALDH1A1HPGDKDM4EMAPTTSHR | |
| SCHEMBL678379 | 0.67 | MEN1 (0.42) | ALDH1A1KDM4ECYP1A2KMT2AMEN1 | |
| SCHEMBL7733127 | 0.67 | MEN1 (0.42) | ALDH1A1KDM4ECYP1A2KMT2AMEN1 | |
| SCHEMBL5468812 | 0.67 | MEN1 (0.42) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL5472185 | 0.67 | MEN1 (0.42) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL7739138 | 0.67 | MEN1 (0.42) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL677747 | 0.67 | MEN1 (0.42) | ALDH1A1KDM4ECYP1A2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007129169-A2 | COX- II INHIBITORS FOR IMPROVING REPRODUCTIVE SUCCESS IN A FEMALE ANIMAL | PFIZER LIMITED (GB) | 2007-11-15 | — | — | WO | disclosed |