Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEK | Q02763 | 17/20 | 0.68 |
| ▸ | KDR | P35968 | 16/20 | 0.68 |
| ▸ | RAF1 | P04049 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5357494 | 0.88 | KDR (0.86) | TEKKDRRAF1 | |
| SCHEMBL5341538 | 0.88 | KDR (0.71) | TEKKDRRAF1 | |
| SCHEMBL5348683 | 0.86 | TEK (0.87) | TEKKDRRAF1 | |
| SCHEMBL5351759 | 0.85 | TEK (0.87) | TEKKDRRAF1 | |
| SCHEMBL5348789 | 0.84 | KDR (0.72) | TEKKDRRAF1 | |
| SCHEMBL5349168 | 0.84 | TEK (0.79) | TEKKDRRAF1 | |
| SCHEMBL5360831 | 0.82 | KDR (0.67) | TEKKDRRAF1 | |
| Hydrochloric Acid SCHEMBL30957043 | 0.82 | KDR (0.82) | TEKKDRRAF1 | |
| Hydrochloric Acid SCHEMBL30957042 | 0.82 | KDR (0.82) | TEKKDRRAF1 | |
| SCHEMBL5341745 | 0.82 | KDR (0.86) | TEKKDRRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249600-A1 | CHEMICAL COMPOUNDS | CHEUNG MUI | 2007-10-25 | — | — | US | claimed |
| US-20040082583-A1 | Chemical compounds | SMITHKLINE BEECHAM CORPORATION | 2004-04-29 | — | — | US | claimed |
| US-20070249600-A1 | CHEMICAL COMPOUNDS | CHEUNG MUI | 2007-10-25 | — | — | US | disclosed |
| US-20070249600-A1 | CHEMICAL COMPOUNDS | CHEUNG MUI | 2007-10-25 | — | — | US | disclosed |
| US-20070249600-A1 | CHEMICAL COMPOUNDS | CHEUNG MUI | 2007-10-25 | — | — | US | disclosed |
| US-7238813-B2 | Chemical compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238813-B2 | Chemical compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238813-B2 | Chemical compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-20040082583-A1 | Chemical compounds | SMITHKLINE BEECHAM CORPORATION | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249600-A1 | CHEMICAL COMPOUNDS | TIE1, KDR, FLT4 | TEK 5/4885KDR 2/4885RAF1 764/4885 |
| US-20040082583-A1 | Chemical compounds | TIE1, KDR, FLT4 | TEK 5/4885KDR 2/4885RAF1 764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.