SCHEMBL535032

SCHEMBL535032

C/C([C]=O)=C(\C)[C]=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11670115 1.00
SCHEMBL16860497 1.00
SCHEMBL2163249 0.82
SCHEMBL1420922 0.82
SCHEMBL22714121 0.76
SCHEMBL1388169 0.74
SCHEMBL6806658 0.71
SCHEMBL17338061 0.71
SCHEMBL6806657 0.71
SCHEMBL2162947 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040097586-A1 Anti-tumor compounds UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) 2004-05-20 US claimed
US-20040014652-A1 Tumor activated prodrug compounds and methods of making and using the same DIATOS SA (FR) 2004-01-22 US claimed
EP-1286700-A2 TUMOR ACTIVATED PRODRUG COMPOUNDS UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) 2003-03-05 EP claimed
WO-2001091798-A2 TUMOR ACTIVATED PRODRUG COMPOUNDS UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) 2001-12-06 WO claimed
WO-1989004672-A1 DERIVATIVES OF LINCOSAMINIDE ANTIBIOTICS THE UPJOHN COMPANY (US) 1989-06-01 WO claimed
CN-111925403-A Glucosamine donors and application thereof 山东大学 2020-11-13 CN disclosed
US-10174132-B2 Heparan sulfate synthesis UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2019-01-08 US disclosed
US-20160060365-A1 HEPARAN SULFATE SYNTHESIS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2016-03-03 US disclosed
US-20140235850-A1 SYNTHESIS OF HMO CORE STRUCTURES GLYCOM A/S (DK) 2014-08-21 US disclosed
US-20120142560-A1 HEPARAN SULFATE SYNTHESIS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2012-06-07 US disclosed
EP-2414371-A2 HEPARAN SULFATE SYNTHESIS The University Of Georgia Research Foundation, Inc (US) 2012-02-08 EP disclosed
US-7964415-B2 Stable water-soluble polyethylenimine conjugates and methods of use thereof CARDIOGENICS INC. (CA) 2011-06-21 US disclosed
US-5214131-A Polyethylene glycol derivatives, modified peptides and production thereof SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1993-05-25 US disclosed
US-5106955-A Reversibly modifying an antibody which decreases its immunoactivity; reacting with a drug, hormone or enzyme; removing the modifier to restore completely the original immunoactivity TEIJIN LIMITED (JP) 1992-04-21 US disclosed
US-5093531-A POLYETHYLENE GLYCOL SUBSTITUTED PHENYL GLYOXALS SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1992-03-03 US disclosed
EP-0400486-A2 Polyethylene glycol derivatives, modified peptides and production thereof SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1990-12-05 EP disclosed
EP-0340741-A2 Polyethylene glycol derivatives, modified peptides and production thereof SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1989-11-08 EP disclosed
EP-0325270-A2 Anticancer conjugates THE GREEN CROSS CORPORATION (JP) 1989-07-26 EP disclosed
WO-1989004672-A1 DERIVATIVES OF LINCOSAMINIDE ANTIBIOTICS THE UPJOHN COMPANY (US) 1989-06-01 WO disclosed
EP-0307480-A1 PROCESS FOR PREPARING ANTIBODY COMPLEX TEIJIN LIMITED (JP) 1989-03-22 EP disclosed