SCHEMBL5352569

SCHEMBL5352569

CCC[C@H]1CC[C@H]([C@H]2CC[C@H](C(=O)Oc3ccc(F)cc3)CC2)CC1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.46
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
F2 P00734 1/20 0.43
ELANE P08246 2/20 0.43
MAPT P10636 1/20 0.41
ATM Q13315 1/20 0.38
FAAH O00519 1/20 0.38
CA2 P00918 1/20 0.37
ALDH1A1 P00352 1/20 0.37
POLB P06746 1/20 0.37
CYP2C9 P11712 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10802459 1.00 KMT2A (0.46) KMT2AHTTSMN1; SMN2TDP1F2
SCHEMBL5352575 1.00 KMT2A (0.46) KMT2AHTTSMN1; SMN2TDP1F2
SCHEMBL5352566 1.00 KMT2A (0.46) KMT2AHTTSMN1; SMN2TDP1F2
SCHEMBL8447872 0.96 KMT2A (0.50) KMT2AHTTSMN1; SMN2TDP1F2
SCHEMBL8052321 0.96 KMT2A (0.50) KMT2AHTTSMN1; SMN2TDP1F2
SCHEMBL11103795 0.92 KMT2A (0.46) KMT2AHTTSMN1; SMN2TDP1F2
SCHEMBL11103787 0.92 KMT2A (0.46) KMT2AHTTSMN1; SMN2TDP1F2
SCHEMBL7511856 0.91 HTT (0.43) KMT2AHTTSMN1; SMN2TDP1F2
SCHEMBL8380862 0.91 HTT (0.43) KMT2AHTTSMN1; SMN2TDP1F2
SCHEMBL8035948 0.91 HTT (0.43) KMT2AHTTSMN1; SMN2TDP1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-56135445-A None JP disclosed
US-7186447-B2 Two plane parallel support plates with frame form cell, with integrated non-linear elements for switching individual picture elements on support plates, and nematic liquid crystal mixture is present in cell, having positive dielectric anisotropy and high resistivity MERCK PATENT GMBH (DE) 2007-03-06 US disclosed
US-20050196551-A1 Matrix liquid crystal display WEBER GEORG (DE) 2005-09-08 US disclosed
US-6905740-B2 The invention relates to a matrix liquid crystal display containing integrated non-linear elements and a liquid crystal mixture which has a particularly high resistivity. MERCK PATENT GMBH (DE) 2005-06-14 US disclosed
US-20030207046-A1 Matrix liquid crystal display MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2003-11-06 US disclosed
US-6562419-B1 Matrix liquid crystal display MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2003-05-13 US disclosed
EP-0700982-B1 A liquid crystal composition and a liquid crystal display element using the same CHISSO CORP (JP) 2000-04-26 EP disclosed
US-6004479-A FLUOROETHERS FOR LIQUID CRYSTAL DISPLAYS AND DIELECTRICS MERCK KGAA (DE) 1999-12-21 US disclosed
US-5958290-A ELECTROOPTICAL APPARATUS WITH DIELECTRIC LIQUID CRYSTALS FOR RADIATION TRANSPARENT MEDIUM MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1999-09-28 US disclosed
EP-0679707-B1 Liquid crystalline compound, liquid crystal composition and liquid crystal display element CHISSO CORP (JP) 1999-06-16 EP disclosed
EP-0281065-B1 LIQUID CRYSTAL COMPOSITION AND DISPLAY ELEMENT CHISSO CORPORATION (JP) 1991-11-27 EP disclosed
WO-1991010716-A1 MATRIX LIQUID CRYSTAL DISPLAY MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1991-07-25 WO disclosed
WO-1991005029-A1 ELECTRO-OPTICAL LIQUID CRYSTAL SYSTEM MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1991-04-18 WO disclosed
EP-0393636-A2 Liquid crystal composition and liquid crystal display using said composition CHISSO CORPORATION (JP) 1990-10-24 EP disclosed
US-4917818-A STEEP VOLTAGE TRANSMITTANCE USED IN WATCHES, ELECTRONIC CALCULATORS CHISSO CORPORATION (JP) 1990-04-17 US disclosed
US-4877549-A HIGH MULTIPLEXING DISPLAY DEVICE CHISSO CORPORATION (JP) 1989-10-31 US disclosed
EP-0318003-A2 A liquid crystal composition for twist nematic mode CHISSO CORPORATION (JP) 1989-05-31 EP disclosed
EP-0306917-A2 A nematic liquid crystal composition CHISSO CORPORATION (JP) 1989-03-15 EP disclosed
EP-0281065-A1 Liquid crystal composition and display element CHISSO CORPORATION (JP) 1988-09-07 EP disclosed
JP-S56135445-A 4\"-HALOGENOPHENYL ESTER OF TRANS-4-(TRANS-4'-SUBSTITUTED CYCLOHEXYL)-CYCLOHEXANECARBOXYLIC ACID CHISSO CORP 1981-10-22 JP disclosed