Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.57 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.57 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.57 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.57 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.57 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.57 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.57 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.57 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | VDR | P11473 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2303738 | 0.89 | GPBAR1 (0.57) | GPBAR1EPHA2AKR1B10AKR1B1EFNA1 | |
| SCHEMBL6825583 | 0.85 | GPBAR1 (0.60) | GPBAR1EPHA2AKR1B10AKR1B1EFNA1 | |
| SCHEMBL6825588 | 0.85 | GPBAR1 (0.60) | GPBAR1EPHA2AKR1B10AKR1B1EFNA1 | |
| SCHEMBL1720094 | 0.85 | GPBAR1 (0.63) | GPBAR1EPHA2AKR1B10AKR1B1EFNA1 | |
| SCHEMBL24896972 | 0.85 | GPBAR1 (0.63) | GPBAR1EPHA2AKR1B10AKR1B1EFNA1 | |
| SCHEMBL24153315 | 0.85 | GPBAR1 (0.59) | GPBAR1AKR1B10AKR1B1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5320085 | 0.84 | GPBAR1 (0.62) | GPBAR1EPHA2AKR1B10AKR1B1EFNA1 | |
| SCHEMBL5395210 | 0.84 | GPBAR1 (0.59) | GPBAR1EPHA2AKR1B10AKR1B1EFNA1 | |
| SCHEMBL29773449 | 0.83 | GPBAR1 (0.58) | GPBAR1EPHA2AKR1B10AKR1B1EFNA1 | |
| SCHEMBL11416283 | 0.82 | GPBAR1 (0.57) | GPBAR1EPHA2AKR1B10AKR1B1EFNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070179100-A1 | Protected monomers | ALNYLAM PHARMACEUTICALS, INC. | 2007-08-02 | — | — | US | disclosed |
| US-7235552-B1 | Cholenic acid amides and pharmaceutical compositions thereof | RESEARCH INSTITUTE FOR MEDICINE AND CHEMISTRY, INC. (US) | 2007-06-26 | — | — | US | disclosed |
| EP-1625138-A2 | PROTECTED MONOMERS | Alnylam Pharmaceuticals Inc. (US) | 2006-02-15 | — | — | EP | disclosed |
| CN-1177860-C | Cholenic acid amide and its medicinal composition | ҽѧ�뻯ѧ�о��� | 2004-12-01 | — | — | CN | disclosed |
| WO-2004094345-A2 | PROTECTED MONOMERS | ALNYLAM PHARMACEUTICALS INC. (US) | 2004-11-04 | — | — | WO | disclosed |
| CN-1292797-A | Cholenic acid amide and its medicinal composition | RES INST MEDICINE CHEM (US) | 2001-04-25 | — | — | CN | disclosed |
| EP-1060188-A1 | CHOLENIC ACID AMIDES AND PHARMACEUTICAL COMPOSITIONS THEREOF | RESEARCH INSTITUTE FOR MEDICINE AND CHEMISTRY INC. (US) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999045024-A1 | CHOLENIC ACID AMIDES AND PHARMACEUTICAL COMPOSITIONS THEREOF | RESEARCH INSTITUTE FOR MEDICINE AND CHEMISTRY INC. (US) | 1999-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070179100-A1 | Protected monomers | PCNA, POLN, PARP1 | GPBAR1 4124/4885EPHA2 4592/4885AKR1B10 2035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.