Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5353165 | 1.00 | TSHR (0.47) | TSHRSLC6A4SLC6A3ALDH1A1DRD2 | |
| SCHEMBL9061221 | 0.96 | TSHR (0.43) | TSHRSLC6A4SLC6A3ALDH1A1DRD2 | |
| SCHEMBL9061189 | 0.96 | TSHR (0.43) | TSHRSLC6A4SLC6A3ALDH1A1DRD2 | |
| SCHEMBL9061208 | 0.96 | TSHR (0.43) | TSHRSLC6A4SLC6A3ALDH1A1DRD2 | |
| SCHEMBL7735492 | 0.92 | TSHR (0.41) | TSHRSLC6A4SLC6A3ALDH1A1DRD2 | |
| SCHEMBL7735497 | 0.92 | TSHR (0.41) | TSHRSLC6A4SLC6A3ALDH1A1DRD2 | |
| SCHEMBL5344231 | 0.91 | TSHR (0.47) | TSHRSLC6A4SLC6A3ALDH1A1DRD2 | |
| SCHEMBL5344223 | 0.91 | TSHR (0.47) | TSHRSLC6A4SLC6A3ALDH1A1DRD2 | |
| SCHEMBL10533715 | 0.89 | TSHR (0.39) | TSHRSLC6A4SLC6A3ALDH1A1DRD2 | |
| SCHEMBL7735160 | 0.88 | TSHR (0.39) | TSHRSLC6A4SLC6A3ALDH1A1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186447-B2 | Two plane parallel support plates with frame form cell, with integrated non-linear elements for switching individual picture elements on support plates, and nematic liquid crystal mixture is present in cell, having positive dielectric anisotropy and high resistivity | MERCK PATENT GMBH (DE) | 2007-03-06 | — | — | US | disclosed |
| US-20050196551-A1 | Matrix liquid crystal display | WEBER GEORG (DE) | 2005-09-08 | — | — | US | disclosed |
| US-6905740-B2 | The invention relates to a matrix liquid crystal display containing integrated non-linear elements and a liquid crystal mixture which has a particularly high resistivity. | MERCK PATENT GMBH (DE) | 2005-06-14 | — | — | US | disclosed |
| US-20030207046-A1 | Matrix liquid crystal display | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2003-11-06 | — | — | US | disclosed |
| US-6562419-B1 | Matrix liquid crystal display | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2003-05-13 | — | — | US | disclosed |
| US-6004479-A | FLUOROETHERS FOR LIQUID CRYSTAL DISPLAYS AND DIELECTRICS | MERCK KGAA (DE) | 1999-12-21 | — | — | US | disclosed |
| EP-0394419-B2 | MATRIX LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 1999-10-06 | — | — | EP | disclosed |
| EP-0438547-B2 | SUPER-TWIST LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 1999-07-07 | — | — | EP | disclosed |
| EP-0494368-B1 | Supertwist liquid crystal display | MERCK PATENT GMBH (DE) | 1999-01-20 | — | — | EP | disclosed |
| EP-0471831-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 1996-08-14 | — | — | EP | disclosed |
| US-5122295-A | Containing liquid crystal mixture with high resistivity | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-06-16 | — | — | US | disclosed |
| EP-0481293-A2 | Supertwist liquid crystal display | MERCK PATENT GmbH (DE) | 1992-04-22 | — | — | EP | disclosed |
| EP-0471831-A1 | LIQUID CRYSTALLINE MEDIUM. | MERCK PATENT GMBH (DE) | 1992-02-26 | — | — | EP | disclosed |
| EP-0462243-A1 | MATRIX LIQUID CRYSTAL DISPLAY. | MERCK PATENT GMBH (DE) | 1991-12-27 | — | — | EP | disclosed |
| WO-1991013947-A2 | LIQUID CRYSTALLINE MEDIUM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-09-19 | — | — | WO | disclosed |
| EP-0438547-A1 | SUPER-TWIST LIQUID CRYSTAL DISPLAY. | MERCK PATENT GMBH (DE) | 1991-07-31 | — | — | EP | disclosed |
| WO-1991010716-A1 | MATRIX LIQUID CRYSTAL DISPLAY | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-07-25 | — | — | WO | disclosed |
| WO-1991000898-A1 | SUPER-TWIST LIQUID CRYSTAL DISPLAY | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-01-24 | — | — | WO | disclosed |
| EP-0394419-A1 | MATRIX LIQUID CRYSTAL DISPLAY. | MERCK PATENT GMBH (DE) | 1990-10-31 | — | — | EP | disclosed |
| WO-1990004623-A1 | MATRIX LIQUID CRYSTAL DISPLAY | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-05-03 | — | — | WO | disclosed |