Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 18/20 | 0.69 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.69 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL408366 | 0.97 | S1PR1 (0.67) | S1PR1S1PR3NR1H4 | |
| SCHEMBL406941 | 0.96 | S1PR1 (0.75) | S1PR1S1PR3NR1H4 | |
| SCHEMBL2773270 | 0.91 | S1PR1 (0.65) | S1PR1S1PR3NR1H4 | |
| SCHEMBL2806562 | 0.89 | S1PR1 (0.72) | S1PR1S1PR3NR1H4 | |
| SCHEMBL2772294 | 0.87 | S1PR1 (0.57) | S1PR1S1PR3NR1H4 | |
| SCHEMBL411050 | 0.87 | S1PR1 (0.81) | S1PR1S1PR3NR1H4 | |
| SCHEMBL2775461 | 0.86 | S1PR1 (0.53) | S1PR1S1PR3NR1H4 | |
| SCHEMBL405422 | 0.86 | S1PR1 (0.62) | S1PR1S1PR3 | |
| SCHEMBL2775209 | 0.86 | S1PR1 (0.59) | S1PR1S1PR3NR1H4 | |
| SCHEMBL2772658 | 0.86 | S1PR1 (0.66) | S1PR1S1PR3NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414341-A2 | OXADIAZOLE DERIVATIVES | Merck Serono SA (CH) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010115751-A2 | OXADIAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2010-10-14 | — | — | WO | disclosed |