SCHEMBL5353750

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5785011	0.90	EGFR (0.54)	EGFRCDK1ABL1PRKCACAMK2D
	Hydrochloric Acid SCHEMBL5351366	0.89	EGFR (0.53)	EGFRCDK1ABL1PRKCACAMK2D
	Hydrochloric Acid SCHEMBL5350968	0.89	EGFR (0.53)	EGFRCDK1ABL1PRKCACAMK2D
	SCHEMBL5361357	0.87	TTBK1 (0.48)	EGFRCDK1ABL1PRKCATTBK1
	SCHEMBL5351369	0.83	EGFR (0.59)	EGFRSRC
	SCHEMBL14355887	0.81	NPC1 (0.46)	EGFRCDK1ABL1PRKCATP53
	SCHEMBL5358394	0.80	EGFR (0.56)	EGFRTTBK1TTBK2SRC
	SCHEMBL4742040	0.79	EGFR (0.49)	EGFRCDK1ERBB2TTBK1TTBK2
	SCHEMBL5362671	0.79	RET (0.47)	EGFRTTBK1LMNA
	SCHEMBL5348597	0.76	TTBK1 (0.49)	EGFRTTBK1TTBK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.