Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 13/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.45 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.45 |
| ▸ | CTSD | P07339 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5354118 | 1.00 | BACE1 (0.46) | BACE1FOLH1BACE2CTSD | |
| SCHEMBL30401136 | 0.93 | FOLH1 (0.51) | BACE1FOLH1BACE2CTSD | |
| SCHEMBL30194119 | 0.89 | BACE1 (0.47) | BACE1FOLH1BACE2CTSD | |
| SCHEMBL29571467 | 0.89 | BACE1 (0.46) | BACE1FOLH1BACE2CTSD | |
| SCHEMBL31232452 | 0.89 | FOLH1 (0.47) | BACE1FOLH1BACE2CTSD | |
| SCHEMBL31753464 | 0.88 | FOLH1 (0.53) | FOLH1 | |
| SCHEMBL30681789 | 0.88 | BACE1 (0.46) | BACE1FOLH1BACE2CTSD | |
| SCHEMBL30681783 | 0.88 | BACE1 (0.46) | BACE1FOLH1BACE2CTSD | |
| SCHEMBL30400254 | 0.87 | FOLH1 (0.54) | FOLH1 | |
| SCHEMBL10336059 | 0.87 | BACE1 (0.51) | BACE1FOLH1BACE2CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7211431-B2 | Expression cassettes for producing plants with increased levels of essential amino acids | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 2007-05-01 | — | — | US | disclosed |
| US-20050010973-A1 | Proteins with increased levels of essential amino acids | PIONEER HI-BRED INTERNATIONAL, INC. | 2005-01-13 | — | — | US | disclosed |
| US-6800726-B1 | DERIVED FROM PROTEASE/CHYMOTRYPSIN INHIBITOR IN PLANTS; FOR FEED/FOODS; NUTRACEUTICALS | PIONEER HI-BRED INTERNATIONAL, INC. | 2004-10-05 | — | — | US | disclosed |
| EP-0946729-A2 | PROTEINS WITH ENHANCED LEVELS OF ESSENTIAL AMINO ACIDS | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998020133-A2 | PROTEINS WITH ENHANCED LEVELS OF ESSENTIAL AMINO ACIDS | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 1998-05-14 | — | — | WO | disclosed |