SCHEMBL5354348

SCHEMBL5354348

C=C(C)C(=O)n1ccc2ccccc21

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 2/20 0.68
TSHR P16473 1/20 0.54
RAB9A P51151 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
GAA P10253 1/20 0.48
MAPK1 P28482 2/20 0.43
KMT2A Q03164 1/20 0.42
TFPI2 P48307 1/20 0.41
NPY4R P50391 1/20 0.41
HTR3E A5X5Y0 1/20 0.40
HTR3B O95264 1/20 0.40
CHRNB2 P17787 1/20 0.40
CHRNA7 P36544 1/20 0.40
CHRNA4 P43681 1/20 0.40
HTR3A P46098 1/20 0.40
HTR3D Q70Z44 1/20 0.40
HTR3C Q8WXA8 1/20 0.40
LMNA P02545 1/20 0.39
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29506395 0.81 NOTUM (1.00) NOTUMTSHRRAB9AL3MBTL1GAA
SCHEMBL41252 0.81 NOTUM (1.00) NOTUMTSHRRAB9AL3MBTL1GAA
Ammonia Solution, Strong SCHEMBL27633395 0.79 NOTUM (0.96) NOTUMTSHRRAB9AL3MBTL1GAA
SCHEMBL2079635 0.78 NOTUM (0.61) NOTUMTSHRRAB9AL3MBTL1GAA
SCHEMBL1151123 0.77 NOTUM (0.70) NOTUMTSHRRAB9AL3MBTL1GAA
SCHEMBL10477477 0.77 NOTUM (0.70) NOTUMTSHRRAB9AL3MBTL1GAA
SCHEMBL23902687 0.75 NOTUM (0.58) NOTUMTSHRRAB9AL3MBTL1GAA
SCHEMBL21841945 0.75 NOTUM (0.58) NOTUMTSHRRAB9AL3MBTL1GAA
SCHEMBL29453277 0.75 TSHR (0.69) NOTUMTSHRRAB9AL3MBTL1GAA
SCHEMBL931955 0.75 TSHR (0.69) NOTUMTSHRRAB9AL3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7202016-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2007-04-10 US disclosed
US-20050214680-A1 Radiation-sensitive resin composition MIYAJI MASAAKI 2005-09-29 US disclosed
US-6933094-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-08-23 US disclosed
US-20020058201-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2002-05-16 US disclosed
EP-1193558-A2 Radiation-sensitive resin composition JSR Corporation (JP) 2002-04-03 EP disclosed