Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 19/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL409995 | 0.88 | S1PR1 (0.62) | S1PR1S1PR3PTPN1 | |
| SCHEMBL410576 | 0.87 | S1PR1 (0.60) | S1PR1S1PR3 | |
| SCHEMBL2774789 | 0.83 | S1PR1 (0.64) | S1PR1S1PR3PTPN1 | |
| SCHEMBL410964 | 0.81 | S1PR1 (0.67) | S1PR1S1PR3 | |
| SCHEMBL2771037 | 0.78 | S1PR1 (0.56) | S1PR1S1PR3PTPN1 | |
| SCHEMBL407012 | 0.78 | S1PR1 (0.70) | S1PR1S1PR3 | |
| SCHEMBL2805557 | 0.76 | S1PR1 (0.59) | S1PR1S1PR3 | |
| SCHEMBL9968865 | 0.76 | S1PR1 (0.63) | S1PR1S1PR3 | |
| SCHEMBL409196 | 0.76 | S1PR1 (0.57) | S1PR1S1PR3 | |
| SCHEMBL13875177 | 0.76 | S1PR1 (0.62) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414341-A2 | OXADIAZOLE DERIVATIVES | Merck Serono SA (CH) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010115751-A2 | OXADIAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2010-10-14 | — | — | WO | disclosed |