SCHEMBL5355072

SCHEMBL5355072

CCCCOc1nc(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2)c(C)c1C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 19/20 0.61
KMT2A Q03164 1/20 0.42
ATM Q13315 1/20 0.42
CNR2 P34972 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5354464 0.85 CNR1 (0.62) CNR1CNR2
SCHEMBL5364853 0.84 CNR1 (0.56) CNR1CNR2
SCHEMBL5358215 0.82 CNR1 (0.63) CNR1CNR2
SCHEMBL5366162 0.80 CNR1 (0.63) CNR1CNR2
SCHEMBL5355862 0.80 CNR1 (0.53) CNR1CNR2
SCHEMBL5355033 0.78 CNR1 (0.44) CNR1CNR2
SCHEMBL5358161 0.76 CNR1 (1.00) CNR1CNR2
SCHEMBL5355070 0.75 CNR1 (1.00) CNR1CNR2
SCHEMBL5354215 0.74 CNR1 (1.00) CNR1CNR2
SCHEMBL5360372 0.73 CNR1 (1.00) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7271266-B2 Substituted 2,3-diphenyl pyridines MERCK & CO., INC. (US) 2007-09-18 US claimed