Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2589264 | 0.80 | RECQL (0.46) | CA14CA12CA2TET2RECQL | |
| SCHEMBL7023795 | 0.78 | CA14 (0.39) | CA14CA12CA2TET2KDM4E | |
| SCHEMBL21070172 | 0.75 | CA14 (0.39) | CA14CA12CA2TET2RECQL | |
| SCHEMBL31485763 | 0.73 | CA14 (0.36) | CA14CA12CA2GAACA1 | |
| SCHEMBL21071237 | 0.72 | KDM4E (0.37) | CA14CA12CA2KDM4ECA1 | |
| SCHEMBL21070174 | 0.72 | KDM4E (0.37) | CA14CA12CA2KDM4ECA1 | |
| SCHEMBL1689401 | 0.70 | HDAC6 (0.37) | CA14CA12CA2GAACA1 | |
| SCHEMBL21071236 | 0.70 | CA12 (0.35) | CA14CA12CA2TET2KDM4E | |
| SCHEMBL5352524 | 0.70 | CA14 (0.40) | CA14CA12CA2TET2RECQL | |
| SCHEMBL3187773 | 0.69 | HDAC6 (0.36) | CA14CA12CA2GAACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223833-B1 | Peptide nucleic acid conjugates | ISIS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| EP-0804456-B1 | PEPTIDE NUCLEIC ACID CONJUGATES | ISIS PHARMACEUTICALS INC (US) | 2002-08-21 | — | — | EP | disclosed |