Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4841915 | 0.93 | CACNA1B (0.59) | CACNA1BKMT2AMEN1HRH3ACKR3 | |
| SCHEMBL5352649 | 0.92 | KMT2A (0.48) | CACNA1BKMT2AMEN1SRCALDH1A1 | |
| SCHEMBL5361323 | 0.86 | CACNA1B (0.61) | CACNA1BHRH3TACR1ALDH1A1 | |
| SCHEMBL5350136 | 0.85 | CACNA1B (0.71) | CACNA1BKMT2AMEN1HRH3SRC | |
| SCHEMBL4843256 | 0.85 | CACNA1B (0.57) | CACNA1BKMT2AHRH3SRCTACR1 | |
| SCHEMBL5361820 | 0.85 | CACNA1B (0.51) | CACNA1BGHSRMCL1HDAC8 | |
| SCHEMBL5350467 | 0.84 | CACNA1B (0.49) | CACNA1BKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL5349400 | 0.84 | CACNA1B (0.49) | CACNA1BKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL5345730 | 0.84 | CACNA1B (0.49) | CACNA1BKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL5345749 | 0.84 | CACNA1B (0.49) | CACNA1BKMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166590-B2 | Amino acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-23 | — | — | US | claimed |
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |
| EP-0997147-A1 | AMINO ACID DERIVATIVES | Ono Pharmaceutical Co., Ltd. (JP) | 2000-05-03 | — | — | EP | claimed |
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | disclosed |
| EP-0997147-A1 | AMINO ACID DERIVATIVES | Ono Pharmaceutical Co., Ltd. (JP) | 2000-05-03 | — | — | EP | disclosed |