SCHEMBL5355965

SCHEMBL5355965

CC(C)N1N=C(C2CCCCC2)c2ccc(O)cc2N(c2ccc(C=O)cc2)C1=O

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTH1R Q03431 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5343663 0.90 PTH1R (0.62) PTH1R
SCHEMBL5344822 0.87 PTH1R (0.53) PTH1R
SCHEMBL5322907 0.87 PTH1R (0.49) PTH1R
SCHEMBL5328196 0.83 PTH1R (0.52) PTH1R
SCHEMBL5329534 0.83 PTH1R (0.48) PTH1R
SCHEMBL5358080 0.82 PTH1R (0.47) PTH1R
SCHEMBL5326300 0.82 PTH1R (0.48) PTH1R
SCHEMBL5350400 0.81 PTH1R (0.51) PTH1R
SCHEMBL5345828 0.81 PTH1R (0.47) PTH1R
SCHEMBL5363678 0.78 PTH1R (0.56) PTH1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007135417-A1 BENZOTRIAZEPINONE DERIVATIVES JAMES BLACK FOUNDATION (GB) 2007-11-29 WO disclosed