Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 12/20 | 0.71 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5359084 | 0.84 | GRIA2 (0.73) | GRIA2GRIA1GRIA3GRIA4CA1 | |
| SCHEMBL5487078 | 0.83 | GRIA2 (0.71) | GRIA2GRIA1GRIA3GRIA4 | |
| SCHEMBL5362165 | 0.83 | GRIA2 (1.00) | GRIA2GRIA1GRIA3GRIA4CA1 | |
| SCHEMBL5362147 | 0.83 | GRIA2 (0.71) | GRIA2GRIA1GRIA3GRIA4CA1 | |
| SCHEMBL5359317 | 0.83 | GRIA2 (0.71) | GRIA2GRIA1GRIA3GRIA4CA1 | |
| SCHEMBL6494353 | 0.83 | GRIA2 (0.70) | GRIA2GRIA1GRIA3GRIA4CA1 | |
| SCHEMBL5358880 | 0.81 | GRIA2 (0.68) | GRIA2GRIA1GRIA3GRIA4CA1 | |
| SCHEMBL5351047 | 0.80 | GRIA2 (0.67) | GRIA2 | |
| SCHEMBL5360533 | 0.80 | GRIA2 (0.66) | GRIA2GRIA1GRIA3GRIA4CA1 | |
| SCHEMBL5351038 | 0.79 | GRIA2 (0.65) | GRIA2GRIA1GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7268129-B2 | Fluorinated benzothiadiazine compounds | LES LABORATOIRES SERVIER (FR) | 2007-09-11 | — | — | US | disclosed |
| CN-1680343-A | New fluorinated benzothiadiazine compounds, a process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-10-12 | — | — | CN | disclosed |
| US-20050165008-A1 | Fluorinated benzothiadiazine compounds | LES LABORATORIES SERVIER (FR) | 2005-07-28 | — | — | US | disclosed |
| EP-1557412-A1 | Fluorinated benzothiadiazine derivatives and their use as AMPA receptor modulators | Les Laboratoires Servier (FR) | 2005-07-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050165008-A1 | Fluorinated benzothiadiazine compounds | GRM1, GRIN1, GRIK5 | GRIA2 50/4885GRIA1 47/4885GRIA3 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.