⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14468438 | 0.77 | — | — | |
| SCHEMBL19718504 | 0.74 | — | — | |
| SCHEMBL171993 | 0.74 | — | — | |
| SCHEMBL27551597 | 0.74 | — | — | |
| SCHEMBL14682064 | 0.74 | — | — | |
| SCHEMBL3847858 | 0.74 | TSHR (0.39) | — | |
| SCHEMBL278725 | 0.73 | — | — | |
| SCHEMBL2650766 | 0.73 | — | — | |
| SCHEMBL2899117 | 0.73 | — | — | |
| SCHEMBL2898495 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186854-B2 | Process for making bicalutamide and intermediates thereof | SYNTHON IP INC. (US) | 2007-03-06 | — | — | US | disclosed |
| EP-1546093-A1 | PROCESS FOR MAKING BICALUTAMIDE AND INTERMEDIATES THEREOF | Synthon B.V. (NL) | 2005-06-29 | — | — | EP | disclosed |
| US-6818766-B2 | USING P-FLUOROBENZENESULFINIC ACID | SYNTHON BV (NL) | 2004-11-16 | — | — | US | disclosed |
| WO-2004031136-A1 | PROCESS FOR MAKING BICALUTAMIDE AND INTERMEDIATES THEREOF | SYNTHON B.V. (NL) | 2004-04-15 | — | — | WO | disclosed |
| US-20040068135-A1 | Process for making bicalutamide and intermediates thereof | SYNTHON IP INC. | 2004-04-08 | — | — | US | disclosed |
| US-20030073742-A1 | Process for making bicalutamide and intermediates thereof | SYNTHON B.V. (NL) | 2003-04-17 | — | — | US | disclosed |