Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.66 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.66 |
| ▸ | TUBB | P07437 | 4/20 | 0.66 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.66 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.66 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.66 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.66 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.66 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.66 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.66 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.66 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.66 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.66 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.66 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.66 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.66 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1367274 | 0.86 | HDAC8 (0.66) | HDAC3TUBB4ATUBBTUBA3CHDAC4 | |
| SCHEMBL5464107 | 0.86 | HDAC8 (0.66) | HDAC3TUBB4ATUBBTUBA3CHDAC4 | |
| SCHEMBL13461615 | 0.83 | PIM1 (0.59) | HDAC3TUBB4ATUBBTUBA3CHDAC4 | |
| SCHEMBL16566438 | 0.82 | HDAC3 (0.64) | HDAC3TUBB4ATUBBTUBA3CHDAC4 | |
| SCHEMBL5462204 | 0.81 | HDAC3 (0.60) | HDAC3TUBB4ATUBBTUBA3CHDAC4 | |
| SCHEMBL14345593 | 0.81 | HDAC8 (0.60) | HDAC3TUBB4ATUBBTUBA3CHDAC4 | |
| SCHEMBL1367877 | 0.80 | HDAC8 (1.00) | HDAC3TUBB4ATUBBTUBA3CHDAC4 | |
| SCHEMBL2143790 | 0.80 | HDAC8 (1.00) | HDAC3TUBB4ATUBBTUBA3CHDAC4 | |
| SCHEMBL2144150 | 0.80 | HDAC8 (1.00) | HDAC3TUBB4ATUBBTUBA3CHDAC4 | |
| SCHEMBL1366285 | 0.80 | HDAC3 (0.61) | HDAC3TUBB4ATUBBTUBA3CHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007143822-A1 | SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | METHYLGENE INC. (CA) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007143822-A1 | SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | METHYLGENE INC. (CA) | 2007-12-21 | — | — | WO | disclosed |
| US-20070293530-A1 | SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | METHYLGENE INC. (CA) | 2007-12-20 | — | — | US | disclosed |
| US-20070293530-A1 | SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | METHYLGENE INC. (CA) | 2007-12-20 | — | — | US | disclosed |
| US-20070293530-A1 | SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | METHYLGENE INC. (CA) | 2007-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293530-A1 | SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC11, HAT1 | HDAC3 4/4885TUBB4A 3491/4885TUBB 1771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.