Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 18/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5326300 | 0.88 | PTH1R (0.48) | PTH1RPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5345828 | 0.87 | PTH1R (0.47) | PTH1RPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5360369 | 0.85 | PTH1R (0.49) | PTH1RPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5349636 | 0.82 | PTH1R (0.47) | PTH1R | |
| SCHEMBL5349639 | 0.82 | PTH1R (0.47) | PTH1R | |
| SCHEMBL5352438 | 0.81 | PTH1R (0.53) | PTH1R | |
| SCHEMBL5350400 | 0.79 | PTH1R (0.51) | PTH1RPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5361888 | 0.76 | PTH1R (0.47) | PTH1RPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5363678 | 0.76 | PTH1R (0.56) | PTH1R | |
| SCHEMBL5322907 | 0.75 | PTH1R (0.49) | PTH1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135417-A1 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-11-29 | — | — | WO | disclosed |