Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | DHODH | Q02127 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL535832 | 0.92 | KMT2A (0.41) | KMT2ADHODHALDH1A1L3MBTL1MEN1 | |
| SCHEMBL17644462 | 0.83 | DHODH (0.43) | KMT2ADHODHMEN1MALT1S1PR1 | |
| SCHEMBL15525072 | 0.82 | DHODH (0.41) | KMT2ADHODHL3MBTL1MEN1MALT1 | |
| SCHEMBL16564047 | 0.81 | DHODH (0.51) | KMT2ADHODHMALT1MAPTNPC1 | |
| SCHEMBL20614137 | 0.81 | DHODH (0.45) | KMT2ADHODHMEN1MALT1MAPT | |
| SCHEMBL16563751 | 0.80 | DHODH (0.48) | DHODHMALT1MAPTSMN1; SMN2LCK | |
| SCHEMBL12911683 | 0.80 | DHODH (0.49) | DHODHMALT1MAPTSMN1; SMN2LCK | |
| SCHEMBL12527833 | 0.80 | DHODH (0.42) | KMT2ADHODHALDH1A1MALT1MAPT | |
| SCHEMBL13072406 | 0.78 | DHODH (0.41) | KMT2ADHODHALDH1A1MALT1NPC1 | |
| SCHEMBL13318558 | 0.78 | DHODH (0.48) | KMT2ADHODHALDH1A1MEN1MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144898-B1 | HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | SUMITOMO CHEMICAL CO (JP) | 2012-02-08 | — | — | EP | disclosed |