Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.52 |
| ▸ | PPARG | P37231 | 15/20 | 0.52 |
| ▸ | PPARD | Q03181 | 5/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5357685 | 1.00 | PPARA (0.52) | PPARAPPARGPPARDLTA4HEPHX2 | |
| SCHEMBL5905403 | 0.97 | PPARA (0.49) | PPARAPPARGPPARDLTA4HEPHX2 | |
| SCHEMBL5905404 | 0.97 | PPARA (0.49) | PPARAPPARGPPARDLTA4HEPHX2 | |
| SCHEMBL5364304 | 0.92 | PPARA (0.52) | PPARAPPARGPPARDEPHX2 | |
| SCHEMBL5364302 | 0.92 | PPARA (0.52) | PPARAPPARGPPARDEPHX2 | |
| SCHEMBL5372533 | 0.90 | PPARA (0.59) | PPARAPPARGPPARDEPHX2 | |
| SCHEMBL5372523 | 0.90 | PPARA (0.59) | PPARAPPARGPPARDEPHX2 | |
| SCHEMBL14501935 | 0.90 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL5360256 | 0.90 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL14501884 | 0.90 | PPARA (0.51) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220880-B2 | Amide linker peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (US) | 2007-05-22 | — | — | US | disclosed |
| US-20060111406-A1 | Amide linker peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (US) | 2006-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111406-A1 | Amide linker peroxisome proliferator activated receptor modulators | PPARG, PPARA, PPARD | PPARA 2/4885PPARG 1/4885PPARD 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.