⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31080344 | 1.00 | — | — | |
| SCHEMBL10836378 | 0.85 | KDM2B (0.38) | — | |
| SCHEMBL10836372 | 0.85 | KDM2B (0.38) | — | |
| SCHEMBL4481298 | 0.84 | — | — | |
| SCHEMBL4476126 | 0.84 | — | — | |
| SCHEMBL4476120 | 0.84 | — | — | |
| SCHEMBL4481295 | 0.84 | — | — | |
| SCHEMBL4476125 | 0.84 | — | — | |
| SCHEMBL9435893 | 0.82 | — | — | |
| SCHEMBL4469185 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747258-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Tenvie Therapeutics, Inc. (US) | 2026-05-27 | — | — | EP | disclosed |
| US-20250136606-A1 | MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE | CARAWAY THERAPEUTICS, INC. (US) | 2025-05-01 | — | — | US | disclosed |
| WO-2025024329-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | NICO THERAPEUTICS, INC. (US) | 2025-01-30 | — | — | WO | disclosed |
| EP-4408850-A1 | MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE | Caraway Therapeutics, Inc. (US) | 2024-08-07 | — | — | EP | disclosed |
| CN-118317963-A | TRPML modulators, compositions thereof, and methods of use | 卡拉韦治疗公司 | 2024-07-09 | — | — | CN | disclosed |
| EP-4317160-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | Kumiai Chemical Industry Co., Ltd. (JP) | 2024-02-07 | — | — | EP | disclosed |
| US-11879109-B2 | Fluorine-containing ether compound, lubricant for magnetic recording medium, and magnetic recording medium | RESONAC CORPORATION (JP) | 2024-01-23 | — | — | US | disclosed |
| CN-114341094-B | Fluorine-containing ether compound, lubricant for magnetic recording medium, and magnetic recording medium | 株式会社力森诺科 | 2024-01-12 | — | — | CN | disclosed |
| CN-117098759-A | Heterocyclic compounds and their use | 组合化学工业株式会社 | 2023-11-21 | — | — | CN | disclosed |
| WO-2023055920-A1 | MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE | CARAWAY THERAPEUTICS, INC. (US) | 2023-04-06 | — | — | WO | disclosed |
| US-6699695-B1 | FOR EXAMPLE, CONVERTING 2-HYDROXY-4-METHYLTHIOBUTYRONITRILE INTO THE CORRESPONDING AMIDE, WHICH IS A PRECURSOR TO THE FEED SUPPLEMENT 2-HYDROXY-4-METHYLTHIOBUTYRIC ACID | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| US-6504044-B2 | Reacting cyclohexanone with the carbanions of an aryl acetonitrile using a base, isolating and purifying 1-(cyano(aryl)methyl) cyclohexanol compound by crystallization | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-01-07 | — | — | US | disclosed |
| EP-1238967-A1 | A process for the preparation of 1-(cyano(aryl)methyl) cyclohexanol | Council of Scientific and Industrial Research (IN) | 2002-09-11 | — | — | EP | disclosed |
| US-20020120164-A1 | Process for the preparation of 1-[cyano(aryl)methyl] cyclohexanol | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2002-08-29 | — | — | US | disclosed |
| EP-1230224-A1 | SUBSTITUTED 5-BENZYL-2,4-DIAMINOPYRIMIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-08-14 | — | — | EP | disclosed |
| US-20020058201-A1 | Radiation-sensitive resin composition | JSR CORPORATION (JP) | 2002-05-16 | — | — | US | disclosed |
| EP-1193558-A2 | Radiation-sensitive resin composition | JSR Corporation (JP) | 2002-04-03 | — | — | EP | disclosed |
| WO-2001032633-A1 | SUBSTITUTED 5-BENZYL-2,4-DIAMINOPYRIMIDINES | BASILEA PHARMACEUTICA AG (CH) | 2001-05-10 | — | — | WO | disclosed |
| CN-1290296-A | Novel microorganisms and process for producing | DAICEL CHEM (JP) | 2001-04-04 | — | — | CN | disclosed |
| EP-1055724-A1 | MICROORGANISMS AND PROCESS FOR PRODUCING AMIDE COMPOUNDS | Daicel Chemical Industries, Ltd. (JP) | 2000-11-29 | — | — | EP | disclosed |