Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 18/20 | 0.46 |
| ▸ | PPARG | P37231 | 17/20 | 0.46 |
| ▸ | PPARD | Q03181 | 12/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5358393 | 0.92 | PPARA (0.49) | PPARAPPARGPPARD | |
| SCHEMBL5360534 | 0.86 | PPARG (0.45) | PPARAPPARGPPARD | |
| SCHEMBL5353991 | 0.86 | PPARG (0.45) | PPARAPPARGPPARDLMNA | |
| SCHEMBL5360502 | 0.82 | PPARA (0.43) | PPARAPPARGPPARDLMNA | |
| SCHEMBL5361854 | 0.81 | PPARG (0.59) | PPARAPPARGPPARD | |
| SCHEMBL5365647 | 0.80 | PPARA (0.48) | PPARAPPARGPPARD | |
| SCHEMBL5363131 | 0.80 | PPARA (0.48) | PPARAPPARGPPARD | |
| SCHEMBL5358157 | 0.79 | PPARA (0.44) | PPARAPPARGPPARDLMNA | |
| SCHEMBL5396376 | 0.78 | PPARA (0.52) | PPARAPPARGPPARD | |
| SCHEMBL5360672 | 0.76 | PPARA (0.46) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220880-B2 | Amide linker peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (US) | 2007-05-22 | — | — | US | claimed |
| US-20060111406-A1 | Amide linker peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (US) | 2006-05-25 | — | — | US | claimed |
| WO-2004000789-A9 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2004-03-11 | — | — | WO | claimed |
| US-7220880-B2 | Amide linker peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (US) | 2007-05-22 | — | — | US | disclosed |
| US-20060111406-A1 | Amide linker peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (US) | 2006-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111406-A1 | Amide linker peroxisome proliferator activated receptor modulators | PPARG, PPARA, PPARD | PPARA 2/4885PPARG 1/4885PPARD 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.