Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.54 |
| ▸ | CASP2 | P42575 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455578 | 0.80 | — | — | |
| SCHEMBL14178258 | 0.79 | EPHX1 (0.42) | EPHX1 | |
| SCHEMBL14178254 | 0.79 | EPHX1 (0.42) | EPHX1 | |
| SCHEMBL14178259 | 0.79 | EPHX1 (0.42) | EPHX1 | |
| SCHEMBL11782207 | 0.78 | EPHX1 (0.62) | EPHX1CASP2ALDH1A1 | |
| SCHEMBL5842289 | 0.78 | EPHX1 (0.56) | EPHX1CASP2ALDH1A1TSHRFAAH | |
| SCHEMBL88539 | 0.77 | EPHX1 (0.54) | EPHX1CASP2ALDH1A1TSHRZDHHC20 | |
| SCHEMBL19957982 | 0.77 | MEN1 (0.65) | EPHX1CASP2ALDH1A1FAAHNAAA | |
| SCHEMBL10960416 | 0.75 | EPHX1 (0.58) | EPHX1CASP2ALDH1A1TSHRFAAH | |
| SCHEMBL10962041 | 0.75 | EPHX1 (0.58) | EPHX1CASP2ALDH1A1TSHRFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007011910-A2 | CHIRAL AMINE-CATALYZED ASYMMETRIC ADDITION OF CARBON-CENTERED NUCLEOPHILES TO IMINES | TRUSTEES OF BOSTON UNIVERSITY (US) | 2007-01-25 | — | — | WO | disclosed |