SCHEMBL5358530

SCHEMBL5358530

COc1c(F)c(F)c(Bc2c(F)c(F)c(OC)c(F)c2F)c(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.34
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5365010 0.95 HSD17B10 (0.32) HSD17B10MEN1KMT2A
SCHEMBL6062210 0.95 HSD17B10 (0.32) HSD17B10MEN1KMT2A
SCHEMBL5347077 0.91 MEN1 (0.32) HSD17B10MEN1KMT2A
SCHEMBL6063597 0.87 MEN1 (0.33) HSD17B10MEN1KMT2A
SCHEMBL5351374 0.87 MEN1 (0.30) MEN1KMT2A
SCHEMBL6062270 0.83 MEN1 (0.32) HSD17B10MEN1KMT2A
SCHEMBL6063238 0.83 MEN1 (0.32) HSD17B10MEN1KMT2A
SCHEMBL6063885 0.83 MEN1 (0.32) HSD17B10MEN1KMT2A
SCHEMBL6062206 0.82 TAAR1 (0.39) HSD17B10MEN1KMT2A
SCHEMBL6063135 0.82 MEN1 (0.31) HSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7217676-B2 Hydrophobization and silica for supported catalyst EXXON MOBIL CHEMICAL PATENTS INC. (US) 2007-05-15 US disclosed
US-20060264320-A1 Hydrophobization and silica for supported catalyst RODRIGUEZ GEORGE 2006-11-23 US disclosed
EP-1704171-A2 HYDROPHOBIZATION AND SILICA FOR SUPPORTED CATALYST ExxonMobil Chemical Patents Inc. (US) 2006-09-27 EP disclosed
WO-2005075526-A2 HYDROPHOBIZATION AND SILICA FOR SUPPORTED CATALYST EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-08-18 WO disclosed
US-20050159299-A1 Hydrophobization and silica for supported catalyst EXXONMOBIL CHEMICAL PATENTS INC. 2005-07-21 US disclosed