Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5369657 | 0.83 | NPSR1 (0.36) | NPSR1TP53KMT2AMEN1POLB | |
| SCHEMBL5354922 | 0.79 | NPSR1 (0.34) | NPSR1KMT2AMEN1POLBKDM4E | |
| SCHEMBL5359272 | 0.78 | NPSR1 (0.40) | NPSR1TP53KMT2AMEN1POLB | |
| SCHEMBL5358401 | 0.75 | NPSR1 (0.35) | NPSR1TP53KMT2AMEN1POLB | |
| SCHEMBL5355287 | 0.70 | GRIA2 (0.43) | NPSR1TP53KMT2AMEN1POLB | |
| SCHEMBL5355691 | 0.70 | GRIA2 (0.43) | NPSR1TP53KMT2AMEN1POLB | |
| SCHEMBL3870262 | 0.70 | GRIA1 (0.36) | NPSR1 | |
| SCHEMBL5358301 | 0.66 | GRIA2 (0.43) | NPSR1TP53KMT2AMEN1POLB | |
| SCHEMBL5352006 | 0.62 | NPSR1 (0.42) | NPSR1TP53KMT2AMEN1POLB | |
| SCHEMBL5356534 | 0.61 | GRIA2 (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7268129-B2 | Fluorinated benzothiadiazine compounds | LES LABORATOIRES SERVIER (FR) | 2007-09-11 | — | — | US | disclosed |
| US-20050165008-A1 | Fluorinated benzothiadiazine compounds | LES LABORATORIES SERVIER (FR) | 2005-07-28 | — | — | US | disclosed |
| EP-1557412-A1 | Fluorinated benzothiadiazine derivatives and their use as AMPA receptor modulators | Les Laboratoires Servier (FR) | 2005-07-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050165008-A1 | Fluorinated benzothiadiazine compounds | GRM1, GRIN1, GRIK5 | NPSR1 132/4885TP53 4216/4885KMT2A 930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.