Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.47 |
| ▸ | PPARG | P37231 | 11/20 | 0.43 |
| ▸ | PPARD | Q03181 | 8/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5357661 | 1.00 | PPARA (0.47) | PPARAPPARGPPARDCTSDSMN1; SMN2 | |
| SCHEMBL5365679 | 1.00 | PPARA (0.47) | PPARAPPARGPPARDCTSDSMN1; SMN2 | |
| SCHEMBL14501921 | 1.00 | PPARA (0.47) | PPARAPPARGPPARDCTSDSMN1; SMN2 | |
| SCHEMBL14501888 | 1.00 | PPARA (0.47) | PPARAPPARGPPARDCTSDSMN1; SMN2 | |
| SCHEMBL14501885 | 1.00 | PPARA (0.47) | PPARAPPARGPPARDCTSDSMN1; SMN2 | |
| SCHEMBL5363074 | 1.00 | PPARA (0.47) | PPARAPPARGPPARDCTSDSMN1; SMN2 | |
| SCHEMBL5358800 | 0.91 | PPARA (0.44) | PPARAPPARGPPARD | |
| SCHEMBL5905529 | 0.87 | PPARA (0.43) | PPARAPPARGPPARD | |
| SCHEMBL5364058 | 0.77 | PPARA (0.68) | PPARAPPARGPPARD | |
| SCHEMBL5364055 | 0.77 | PPARA (0.68) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220880-B2 | Amide linker peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (US) | 2007-05-22 | — | — | US | disclosed |
| US-20060111406-A1 | Amide linker peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (US) | 2006-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111406-A1 | Amide linker peroxisome proliferator activated receptor modulators | PPARG, PPARA, PPARD | PPARA 2/4885PPARG 1/4885PPARD 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.