Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.42 |
| ▸ | PPARG | P37231 | 12/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PTPRF | P10586 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5905530 | 0.96 | PPARA (0.41) | PPARAPPARGRAB9APTPRFPTPN2 | |
| SCHEMBL5363076 | 0.89 | PPARA (0.47) | PPARAPPARGPPARD | |
| SCHEMBL5356972 | 0.86 | PPARA (0.54) | PPARAPPARGPPARD | |
| SCHEMBL5356968 | 0.86 | PPARA (0.54) | PPARAPPARGPPARD | |
| SCHEMBL5358800 | 0.80 | PPARA (0.44) | PPARAPPARGPTPRFPTPN2PTPN1 | |
| SCHEMBL5905529 | 0.77 | PPARA (0.43) | PPARAPPARGPTPRFPTPN2PTPN1 | |
| SCHEMBL5372956 | 0.75 | PPARA (0.55) | PPARAPPARGRAB9APPARD | |
| SCHEMBL5372953 | 0.75 | PPARA (0.55) | PPARAPPARGRAB9APPARD | |
| SCHEMBL5364304 | 0.74 | PPARA (0.52) | PPARAPPARGPPARD | |
| SCHEMBL5364302 | 0.74 | PPARA (0.52) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220880-B2 | Amide linker peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (US) | 2007-05-22 | — | — | US | disclosed |