Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919552 | 0.77 | KMT2A (0.57) | HRH3 | |
| SCHEMBL30466612 | 0.76 | MAPT (0.70) | MAPTALDH1A1HDAC6KDM4E | |
| SCHEMBL28366489 | 0.76 | MAPT (0.70) | MAPTALDH1A1HDAC6KDM4E | |
| SCHEMBL5321848 | 0.76 | GRM2 (0.49) | MAPTGRM2DRD4ALDH1A1DRD2 | |
| SCHEMBL5328000 | 0.75 | GRM2 (0.55) | GRM2DRD4DRD2DRD3 | |
| SCHEMBL5327996 | 0.75 | GRM2 (0.55) | GRM2DRD4DRD2DRD3 | |
| SCHEMBL5324285 | 0.75 | GRM2 (0.55) | GRM2DRD4DRD2DRD3 | |
| SCHEMBL5325773 | 0.75 | GRM2 (0.55) | GRM2DRD4DRD2DRD3 | |
| SCHEMBL5325461 | 0.75 | GRM2 (0.57) | GRM2DRD4DRD2DRD3 | |
| SCHEMBL5326833 | 0.75 | GRM2 (0.57) | GRM2DRD4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135527-A2 | BENZIMIDAZOLYL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | disclosed |