Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4924626 | 0.86 | MAPT (0.76) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5354225 | 0.84 | MAPT (0.57) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5360478 | 0.84 | GAA (0.69) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL14345640 | 0.81 | MAPT (0.57) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5412989 | 0.80 | MAPT (0.51) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4402426 | 0.79 | GAA (0.69) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5392676 | 0.77 | MAPT (0.48) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4926060 | 0.76 | MAPT (1.00) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL2878304 | 0.75 | MAPT (0.53) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4919978 | 0.75 | MAPT (0.67) | MAPTALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138110-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |