Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 20/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4816177 | 0.85 | CCR1 (0.51) | CCR1CYP2C19KCNH2 | |
| SCHEMBL4819063 | 0.85 | CCR1 (0.51) | CCR1CYP2C19KCNH2 | |
| SCHEMBL5360528 | 0.83 | CCR1 (0.58) | CCR1CYP2C19KCNH2 | |
| SCHEMBL4818150 | 0.79 | CCR1 (0.54) | CCR1CYP2C19KCNH2 | |
| SCHEMBL4819411 | 0.78 | CCR1 (0.55) | CCR1CYP2C19KCNH2 | |
| SCHEMBL4817326 | 0.78 | CCR1 (0.59) | CCR1CYP2C19KCNH2 | |
| SCHEMBL4824455 | 0.74 | CCR1 (0.57) | CCR1CYP2C19KCNH2 | |
| SCHEMBL4813415 | 0.71 | CCR1 (0.67) | CCR1CYP2C19KCNH2 | |
| SCHEMBL4816266 | 0.71 | CCR1 (0.59) | CCR1CYP2C19KCNH2 | |
| SCHEMBL13024407 | 0.71 | CCR1 (1.00) | CCR1CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007027734-A2 | BICYCLIC AND BRIDGED NITROGEN HETEROCYCLES | CHEMOCENTRYX, INC. (US) | 2007-03-08 | — | — | WO | disclosed |